Comparing 15D and SF-6D performance in fragility wrist and hip fracture patients in a two-year follow-up case-control study

Value Health. 2012 Dec;15(8):1100-7. doi: 10.1016/j.jval.2012.08.2200. Epub 2012 Oct 25.


Objectives: To examine and compare the two utility and health-related quality-of-life (HRQOL) measures 15D and (SF-6D) in fragility wrist and hip fracture patients and controls, study the responsiveness of 15D and SF-6D, and examine the impact of these fractures on changes in 15D and SF-6D scores over 2 years.

Methods: A total of 152 wrist fracture patients and 164 controls and 61 hip fracture patients and 61 controls with 15D and SF-6D scores were studied.

Results: The mean 15D score decreased significantly in wrist fracture patients between baseline and 2-year follow-up (P=0.003). A wrist fracture was a significant predictor of a decrease in 15D scores 2 years after fracture (B=-0.016; P=0.049), along with low body mass index (B=-0.002; P=0.009). In hip fracture patients, both 15D and SF-6D scores decreased significantly (P<0.001). A hip fracture was a significant predictor of a decrease in 15D (B=-0.060; P=0.001) and SF-6D (B=-0.096; P=0.001) scores.

Conclusions: Our data suggest that a fragility wrist fracture has a long-term negative effect on HRQOL, but not as strong as for fragility hip fractures. 15D seems to be more responsive than SF-6D when assessing HRQOL in patients with fragility fractures.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Body Mass Index
  • Case-Control Studies
  • Female
  • Follow-Up Studies
  • Health Behavior
  • Hip Fractures / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Osteoporotic Fractures / physiopathology*
  • Psychometrics
  • Quality of Life*
  • Socioeconomic Factors
  • Surveys and Questionnaires*
  • Time Factors
  • Wrist Injuries / physiopathology*