Adaptogens in mental and behavioral disorders

Psychiatr Clin North Am. 2013 Mar;36(1):49-64. doi: 10.1016/j.psc.2012.12.005.


This article focuses on the most extensively studied adaptogens: Rhodiola rosea, Eleutherococcus senticosus, and Schisandra chinensis. Clinical studies, evidence for stress-protective and simulative effects, and molecular mechanisms of action on metabolic and other processes regulated by the neuroendocrine system are discussed.

Publication types

  • Review

MeSH terms

  • Clinical Trials as Topic
  • Humans
  • Mental Disorders / drug therapy*
  • Mental Fatigue / drug therapy*
  • Phytotherapy*
  • Stress, Physiological / drug effects*