Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2013 Oct;88(1):144-53.
doi: 10.1016/j.critrevonc.2013.03.007. Epub 2013 Apr 25.

Design of Oncology Clinical Trials: A Review

Affiliations
Review

Design of Oncology Clinical Trials: A Review

Revathi Ananthakrishnan et al. Crit Rev Oncol Hematol. .

Abstract

Cancer is a disease that occurs due to the uncontrolled multiplication of cells that invade nearby tissues and can spread to other parts of the body. An increased incidence of cancer in the world has led to an increase in oncology research and in the number of oncology trials. Well designed oncology clinical trials are a key part of developing effective anti-cancer drugs. This review focuses on statistical considerations in the design and analysis of oncology clinical trials.

Keywords: II and III oncology clinical trials; PK/PD modeling; Phases I; Safety and efficacy endpoints; Statistical analyses; Trial designs.

Similar articles

See all similar articles

Cited by 6 articles

See all "Cited by" articles

MeSH terms

LinkOut - more resources

Feedback