Effects of myrrh on intra-oral mucosal wounds compared with tetracycline- and chlorhexidine-based mouthwashes

Clin Cosmet Investig Dent. 2011 Aug 30:3:53-8. doi: 10.2147/CCIDEN.S24064. Print 2011.


Aim: To evaluate the effect of myrrh compared with chlorhexidine gluconate- and tetracycline-containing mouthwashes on wound healing over time in an animal model.

Methods: A unilateral incision on the right buccal mucosa was made, and the wound was irrigated with myrrh-, chlorhexidine gluconate-, or tetracycline-based mouthwashes at various time intervals. Clinical and histological examination was performed for all the groups.

Results: It was found that the myrrh suspension promotes healing and repair of damaged tissue when used over a short period of time (less than 2 weeks) and in a low-concentration suspension; however, it can have harmful effects if used in excess or over a long period of time.

Conclusion: Further studies will also be required to study these effects and their mechanism of action in detail.

Keywords: chlorhexidine gluconate; mouthwash; myrrh; tetracycline; wound healing.