Intracranial pseudolymphoma presenting with grand mal seizures

J Clin Neurosci. 2014 May;21(5):874-6. doi: 10.1016/j.jocn.2013.06.025. Epub 2013 Sep 11.


Primary central nervous system lymphoproliferative disorders comprise a heterogenous group of intracranial disease, predominantly of the high-grade non-Hodgkin's lymphoma type. We report a 56-year-old woman who developed new-onset grand mal seizures and was found to have two small uniformly enhancing dural-based lesions, which were radiologically concerning for meningiomas. Biopsy demonstrated findings consistent with benign, reactive lymphoid tissue. The patient's seizures resolved post-operatively. To our knowledge, this is the first reported patient with intracranial pseudolymphoma presenting as grand mal seizures. This case highlights this rare differential consideration in a patient with symptomatic dural-based lesion.

Keywords: Intracranial pseudolymphoma; Meningioma; Neuroradiology; Seizure.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / complications
  • Brain Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Epilepsy, Tonic-Clonic / diagnosis*
  • Epilepsy, Tonic-Clonic / etiology
  • Female
  • Humans
  • Middle Aged
  • Pseudolymphoma / complications
  • Pseudolymphoma / diagnosis*