The cerebellotectal pathway in the grey squirrel

Exp Brain Res. 1986;65(1):200-12. doi: 10.1007/BF00243843.

Abstract

In the well laminated superior colliculus of the grey squirrel the cells of origin of the crossed descending pathway to the brainstem gaze centers are contained within the inner sublamina of the intermediate grey layer. The technique of anterograde transport of horseradish peroxidase was used to determine whether the pathway from the cerebellum to the superior colliculus terminates in this region. The technique of retrograde transport of horseradish peroxidase was used to localize the source of this pathway within the cerebellum and to determine the morphology of the cerebellotectal neurons. The grey squirrel cerebellotectal pathway provides two terminal fields to the superior colliculus: a diffuse projection into the deep grey layer and a more concentrated, interrupted projection into the inner sublamina of the intermediate grey layer. The more concentrated projection overlies precisely the tectal sublamina that contains the cells of origin of the predorsal bundle. In contrast to animals with frontal eyes, the cerebellotectal pathway in the grey squirrel was found to project almost entirely contralaterally and the vast majority of the cells of origin for the pathway were distributed ventrally, in the caudal pole of the posterior interpositus nucleus and the adjacent region of the dentate. The labelled cells in both cerebellar nuclei were large and displayed similar morphologies.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cerebellum / cytology*
  • Horseradish Peroxidase
  • Neural Pathways / cytology
  • Sciuridae / anatomy & histology*
  • Superior Colliculi / cytology*
  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins

Substances

  • Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate
  • Wheat Germ Agglutinins
  • Horseradish Peroxidase