Cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas

Lili Yang; Jun Dai; Ying Xiao; Henghui Cheng; Qiurong Ruan

doi:10.1016/j.athoracsur.2013.05.111

Cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas

Ann Thorac Surg. 2014 Feb;97(2):687-9. doi: 10.1016/j.athoracsur.2013.05.111.

Authors

Lili Yang¹, Jun Dai¹, Ying Xiao¹, Henghui Cheng¹, Qiurong Ruan²

Affiliations

¹ Institute of Pathology of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Institute of Pathology of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address: ruanqiurong@sina.com.

PMID: 24484810
DOI: 10.1016/j.athoracsur.2013.05.111

Abstract

We describe for the first time a rare coexistence of a cardiac cavernous hemangioma with multiple pulmonary cavernous hemangiomas. Computed tomography revealed bilateral pulmonary nodules, left pleural effusion, and pericardial effusion. Positron emission tomography showed a pericardial neoplasm. Pathologically, multiple large dilated vascular spaces, lined by a single layer of endothelial cells and filled with blood, were revealed in both the cardiac tumor and the pulmonary nodules. Immunohistochemical examination of the lining cells showed positivity for CD31, FLI1, FVIII, and CD34. Taken together, these findings led to the diagnosis of cardiac cavernous hemangioma and multiple pulmonary cavernous hemangiomas.

Keywords: 11; 18.

Publication types

Case Reports

MeSH terms

Adult
Heart Neoplasms / pathology*
Hemangioma, Cavernous / pathology*
Humans
Lung Neoplasms / pathology*
Male
Neoplasms, Multiple Primary / pathology*