Recommendations for the treatment of osteomyelitis

Braz J Infect Dis. 2014 Sep-Oct;18(5):526-34. doi: 10.1016/j.bjid.2013.12.005. Epub 2014 Apr 1.


With the advances in surgical treatment, antibiotic therapy and the current resources for accurate diagnosis and differentiated approaches to each type of osteomyelitis, better results are being obtained in the treatment of this disease. After a careful literature review carried out by a multiprofessional team, some conclusions were made in order to guide medical approach to different types of osteomyelitis, aiming to obtain better clinical outcomes and reducing the social costs of this disease. Acute and chronic osteomyelitis are discussed, with presentation of the general epidemiological concepts and the commonly used classification systems. The main guidelines for the clinical, laboratory and imaging diagnosis of infections are discussed, as well as the guidelines for surgical and antimicrobial treatments, and the role of hyperbaric oxygen as adjuvant therapy.

Keywords: Bone and joint infection; Infectious diseases; Osteomyelitis; Soft tissue infection.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Acute Disease
  • Anti-Bacterial Agents / therapeutic use*
  • Chronic Disease
  • Combined Modality Therapy
  • Humans
  • Hyperbaric Oxygenation*
  • Osteomyelitis / diagnosis*
  • Osteomyelitis / therapy*


  • Anti-Bacterial Agents