Reversal of dopamine extravasation injury with topical nitroglycerin ointment

Plast Reconstr Surg. 1989 Nov;84(5):811-3. doi: 10.1097/00006534-198911000-00017.

Abstract

We treated a neonate with two sites of ischemia caused by dopamine extravasation. Standard treatment called for local infiltration of phentolamine, an alpha blocker. Instead, we applied 2% topical nitroglycerin ointment and the ischemia was totally reversed.

Publication types

  • Case Reports

MeSH terms

  • Administration, Topical
  • Dopamine / adverse effects*
  • Dopamine / therapeutic use
  • Extravasation of Diagnostic and Therapeutic Materials / complications*
  • Humans
  • Infant, Newborn
  • Ischemia / chemically induced*
  • Nitroglycerin / administration & dosage
  • Nitroglycerin / therapeutic use*
  • Skin / blood supply*

Substances

  • Nitroglycerin
  • Dopamine