Practical application of flavonoid-poor menu meals to the study of the bioavailability of bilberry anthocyanins in human subjects

Biosci Biotechnol Biochem. 2014;78(10):1748-52. doi: 10.1080/09168451.2014.932667. Epub 2014 Jul 7.


Practical application of flavonoid-poor menus was evaluated on the bioavailability of anthocyanins as model flavonoids. Detectable amounts of flavonoids were not found in plasma and urine collected from 13 participants, who took the menus. After ingesting bilberry anthocyanins (919 μmol), average plasma AUC0-6h, Cmax, Tmax values and urinary recovery were 386.0 nmol h/mL, 139.1 nM, 1.31 h and 0.21%, respectively.

Keywords: bilberry anthocyanins; bioavailability; dietary reference intake; flavonoid-poor menu meals; human study.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anthocyanins / blood
  • Anthocyanins / pharmacokinetics*
  • Anthocyanins / urine
  • Biological Availability
  • Flavonoids / analysis*
  • Humans
  • Male
  • Meals*
  • Time Factors
  • Vaccinium myrtillus / chemistry*


  • Anthocyanins
  • Flavonoids