[Bilateral herpetic keratouveitis in an immunocompetent patient]

Arch Soc Esp Oftalmol. 2015 Jan;90(1):30-2. doi: 10.1016/j.oftal.2014.01.008. Epub 2014 Nov 15.
[Article in Spanish]


Case report: We report the case of an immunocompetent male who presented with a limbal-adjacent scleritis and interstitial keratitis in the left eye. A few days later a new dendritiform ulcer in his right eye and bilateral progressive worsening with granulomatous uveitis in both eyes were observed. A thorough review of systems revealed positive serum IgM titles for herpes simplex virus.

Discussion: In the context of a bilateral keratouveitis refractory to conventional treatment it is mandatory to rule out the herpetic origin based on the different forms of clinical presentation of this virus.

Keywords: Herpes; Herpetic keratitis; Herpetic keratouveitis; Keratitis; Queratitis; Queratitis herpética; Queratouveitis herpética; Uveitis.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Adult
  • Antibodies, Viral / blood
  • Antiviral Agents / therapeutic use
  • Corneal Opacity / etiology
  • Corneal Ulcer / etiology
  • Granuloma / etiology
  • Humans
  • Immunocompetence
  • Immunoglobulin M / blood
  • Keratitis, Herpetic / diagnosis*
  • Keratitis, Herpetic / drug therapy
  • Keratitis, Herpetic / immunology
  • Male
  • Scleritis / etiology
  • Simplexvirus / immunology
  • Simplexvirus / physiology
  • Uveitis / etiology*
  • Virus Activation


  • Antibodies, Viral
  • Antiviral Agents
  • Immunoglobulin M
  • Acyclovir