A case of fluoxetine-induced serum sickness

Am J Psychiatry. 1989 Dec;146(12):1616-7. doi: 10.1176/ajp.146.12.1616.


After 3-4 weeks of taking fluoxetine for depression, a 27-year-old man developed fever, skin eruptions, arthralgia, and lymphadenopathy. His clinical symptoms and results of laboratory assessment were consistent with a diagnosis of serum sickness reaction to the fluoxetine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Depressive Disorder / drug therapy
  • Drug Hypersensitivity / etiology
  • Fluoxetine / adverse effects*
  • Humans
  • Male
  • Serum Sickness / chemically induced*


  • Fluoxetine