Biomechanical analyses of the stress distribution and the force transfer in the human knee are essential to better understand the aetiology of joint diseases. Accuracy studies of commonly used capacitive or resistive-based stress distribution measurement systems have led to severe problems caused by an inaccurate experimental setup. For instance, in one study, overestimations of the measured forces in the sensor's centre were reported. Therefore, the primary aim of this study was to investigate the ability of capacitive and resistive-based sensors to measure forces in a homogenous pressure environment and the secondary goal was to analyse the influence of different calibration materials on the measurement accuracy. A Novel pressure vessel and metal indenters covered with different rubber materials were used in combination with a material testing machine to load the sensors. Four different linearly increasing nominal forces (925-3670 N) were applied and the deviations between the nominal and the measured forces were calculated. The capacitive measurement system showed errors between 1% and 7% in the homogenous pressure environment, whereas the errors of the resistive system were found to vary between 4% and 17%. The influence of the calibration material was observed to be greater for the resistive sensors (1-179%) than for the capacitive sensors (0.5-25%). In conclusion, it can be stated that - for the pressure measurement systems compared in this article - the capacitive one is less sensitive to the calibration method and the calibration material than the resistive system.