Acquired color vision deficiency

Surv Ophthalmol. 2016 Mar-Apr;61(2):132-55. doi: 10.1016/j.survophthal.2015.11.004. Epub 2015 Nov 30.


Acquired color vision deficiency occurs as the result of ocular, neurologic, or systemic disease. A wide array of conditions may affect color vision, ranging from diseases of the ocular media through to pathology of the visual cortex. Traditionally, acquired color vision deficiency is considered a separate entity from congenital color vision deficiency, although emerging clinical and molecular genetic data would suggest a degree of overlap. We review the pathophysiology of acquired color vision deficiency, the data on its prevalence, theories for the preponderance of acquired S-mechanism (or tritan) deficiency, and discuss tests of color vision. We also briefly review the types of color vision deficiencies encountered in ocular disease, with an emphasis placed on larger or more detailed clinical investigations.

Keywords: acquired color vision deficiency; color perimetry; color vision deficiency; color vision testing; dyschromatopsia.

Publication types

  • Review

MeSH terms

  • Color Perception Tests
  • Color Vision / physiology
  • Color Vision Defects / epidemiology
  • Color Vision Defects / etiology*
  • Color Vision Defects / physiopathology
  • Humans
  • Retinal Cone Photoreceptor Cells / physiology
  • Visual Field Tests