Cryolipolysis versus laser lipolysis on adolescent abdominal adiposity

Lasers Surg Med. 2016 Apr;48(4):365-70. doi: 10.1002/lsm.22475. Epub 2016 Jan 21.


Background: Noninvasive body contouring is one of the fastest growing segments of the cosmetic aesthetic industry. There is increased public demand for procedures with fewer side effects and shorter recovery times. Cryolipolysis and Laser lipolysis have been used as treatments for localized body contouring.

Objective: To compare the effect of Cryolipolysis versus Laser lipolysis on adolescent's abdominal adiposity.

Design: Randomized, controlled trial.

Subjects: Forty-five obese adolescents of both sexes ranged in age from 13 to 16 years participated in this study were to be categorized into three groups of equal number (each group 15 subjects) randomly selected from population.

Methods: Participants were randomly assigned to three groups. Group A was received (Cryolipolysis and diet), Group B was received (Laser lipolysis and diet), Group C was received (only diet) all groups were observed for 8 weeks. Weight and height scale for (change in weight), tape measurement for (waist-hip ratio), skinfold caliper, and MRI.

Results: There was no significant difference between three groups post-treatment in BMI and body weight P-value were (0.2, 0.42, 0.67), respectively. There was a significant improvement for Cryolipolysis group in waist-hip ratio, Suprailiac skin fold, and subcutaneous adipose tissue than other groups P-value (0.001).

Conclusions: Cryolipolysis has a favorable effect than Laser lipolysis in the reduction of waist-hip ratio, skin folds at Suprailiac level and subcutaneous adipose tissue (SAT), there is no significant difference between them in the reduction of BMI and body weight. All groups did not have an effect on VAT.

Keywords: abdominal adiposity; cryolipolysis; laser lipolysis; subcutaneous adipose tissue.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Combined Modality Therapy
  • Cryosurgery*
  • Female
  • Humans
  • Lipectomy / methods*
  • Low-Level Light Therapy*
  • Male
  • Obesity, Abdominal / diet therapy
  • Obesity, Abdominal / radiotherapy*
  • Obesity, Abdominal / surgery*
  • Pediatric Obesity / diet therapy
  • Pediatric Obesity / radiotherapy*
  • Pediatric Obesity / surgery*
  • Single-Blind Method
  • Subcutaneous Fat, Abdominal / radiation effects
  • Subcutaneous Fat, Abdominal / surgery
  • Treatment Outcome