[The role of large granular lymphocytes of the blood in the differential diagnosis of mediastinal neoplasms]

Klin Khir (1962). 1989:(5):46-7.
[Article in Russian]


Examined were 57 patients with teratomas, cysts, lymphoepithelial and malignant thymomas. One hundred donors of the blood served as a control. In the blood of the normal subjects, (0.315 +/- 0.014) X 10(9)/L of large granule-containing lymphocytes were revealed, in patients with benign tumours--(0.2 +/- 0.02) X 10(9)/L, with lymphoepithelial thymomas--(0.037 +/- 0.004) X 10(9)/L. The data obtained indicate the increased immune depression in the organism in development of tumour process, and depend on degree of its malignization.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Diagnosis, Differential
  • Female
  • Humans
  • Killer Cells, Natural*
  • Leukocyte Count*
  • Male
  • Mediastinal Neoplasms / blood*
  • Middle Aged
  • Teratoma / blood
  • Thymoma / blood
  • Thymus Neoplasms / blood