Review and analysis of physical exercise at hormonal and brain level, and its influence on appetite

Clin Investig Arterioscler. 2017 Nov-Dec;29(6):265-274. doi: 10.1016/j.arteri.2017.04.002. Epub 2017 Jul 29.
[Article in English, Spanish]


Due to the currently growing rate of obesity, it is important to maintain good control of food intake. The main purpose of the present study is to determine the influence of physical exercise on appetite, changes in hormone concentrations, and changes in certain neuronal regions. To achieve this, a literature search was conducted using different data bases. The results show how exercise produces changes in the appetite perception, in the amount of energy intake, and in different weight-control related hormones, as well as in specific neuronal responses. In conclusion, it can be shown that exercise leads to changes in appetite, hunger, and energy intake. In addition, exercise decreases the ghrelin levels and increases concentrations of leptin. Likewise, it is shown how physical exercise alters the responses of certain neuronal regions after visualizing specific food elements decreasing so the appetite or the intake of them.

Keywords: Apetito; Appetite; Consumo de energía; Ejercicio físico; Energy intake; Hormonas; Hormones; Physical exercise.

Publication types

  • Review

MeSH terms

  • Appetite / physiology*
  • Brain / physiology*
  • Eating / physiology
  • Energy Intake / physiology
  • Exercise / physiology*
  • Ghrelin / metabolism
  • Hormones / metabolism
  • Humans
  • Leptin / metabolism
  • Obesity / epidemiology


  • Ghrelin
  • Hormones
  • Leptin