[Jaundice and liver injury with cholestatic pattern after treatment with Metoprololsuccinat]

Ugeskr Laeger. 2017 Dec 18;179(51):V09170698.
[Article in Danish]


Drug-induced liver injury is a well-known adverse event to numerous medications with clinical presentations from asymptomatic liver enzyme elevation to liver failure. However, liver injury after administration with metoprolol is not common, and only few case reports have been published. This is a case report of an 80-year-old woman with liver injury with cholestatic pattern and jaundice after two months of treatment with Metoprololsuccinat. With no evidence of other disease, liver function normalized in the following months after discontinuation of Metoprololsuccinat.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Arrhythmia Agents / administration & dosage
  • Anti-Arrhythmia Agents / adverse effects*
  • Anti-Arrhythmia Agents / therapeutic use
  • Chemical and Drug Induced Liver Injury / etiology*
  • Female
  • Humans
  • Jaundice / chemically induced*
  • Metoprolol / administration & dosage
  • Metoprolol / adverse effects*
  • Metoprolol / therapeutic use


  • Anti-Arrhythmia Agents
  • Metoprolol