Conserved Functional Dynamics: I Like to Move It, Move It!

Structure. 2018 Mar 6;26(3):371-373. doi: 10.1016/j.str.2018.02.010.


The catalytic activities of enzymes are typically associated with their unique structures. However, structural dynamics may also play a functional role in enzyme catalysis. In support of this idea, Narayanan et al. (2018) show in this issue of Structure that enzymes are characterized by the presence of evolutionarily conserved dynamic traits.

Publication types

  • Comment

MeSH terms

  • Biological Evolution*
  • Catalysis
  • Enzymes* / metabolism


  • Enzymes