Choroidal Tuberculoma Manifesting in A Patient of Eales Disease 6 Years after Initial Presentation

Ocul Immunol Inflamm. 2020;28(1):100-102. doi: 10.1080/09273948.2018.1536792. Epub 2018 Oct 19.


Purpose: To describe a case of choroidal tubercle in a patient with Eales disease after 6 years, whose initial work-ups were negative for systemic diseases.Methods: A retrospective chart reviewResults: This case report describes a 39-year-old male with a 6-year history of Eales disease characterized by recurrent inflammations and vitreous hemorrhages in his both eyes. His systemic work-up at the initial presentation was normal which included a negative Mantoux test and a normal chest X-ray. On a follow-up visit after 6 years, fundus examination of the right eye revealed a choroidal tuberculoma and subsequent investigations revealed a positive Mantoux test, QuantiFERON TB Gold test and lymphadenopathy in high-resolution computerized tomography. The choroidal tuberculoma responded well to anti-tubercular treatment and oral steroid.Conclusions: Ocular tuberculosis can be associated with Eales disease and often manifest later in the course of the disease.

Keywords: Eales disease; anti-tubercular treatment; choroidal tubercle; periphlebitis; tuberculosis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antitubercular Agents / therapeutic use
  • Choroid Diseases / diagnosis*
  • Choroid Diseases / drug therapy
  • Fluorescein Angiography
  • Glucocorticoids / therapeutic use
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Methotrexate / therapeutic use
  • Neovascularization, Pathologic / diagnosis*
  • Neovascularization, Pathologic / drug therapy
  • Retinal Vasculitis / diagnosis*
  • Retinal Vasculitis / drug therapy
  • Retrospective Studies
  • Slit Lamp Microscopy
  • Tuberculin Test
  • Tuberculoma / diagnosis*
  • Tuberculoma / drug therapy
  • Tuberculosis, Ocular / diagnosis*
  • Tuberculosis, Ocular / drug therapy
  • Visual Acuity / physiology


  • Antitubercular Agents
  • Glucocorticoids
  • Immunosuppressive Agents
  • Methotrexate

Supplementary concepts

  • Eales disease