Testing the Effects of Dietary Seafood Consumption on Depressive Symptoms

Methods Mol Biol. 2020:2138:233-242. doi: 10.1007/978-1-0716-0471-7_15.

Abstract

This chapter presents a protocol for assessing the effects dietary seafood consumption on depressive symptoms. We designed a cross-sectional study of 206 participants recruited in two Torres Strait Island communities. Depressive symptoms were assessed using the adapted Patient Health Questionnaire-9 (aPHQ-9), diet was analyzed with a structured questionnaire, omega-3 and omega-6 fatty acid concentrations were measured via a capillary dried blood spot system, and plasma levels of triglycerides and cholesterol were measured by gas-phase chromatography. Finally, we tested the relationship between seafood consumption, blood lipid concentrations, and depression scores using independent samples t-tests and a logistic and quantile regression model.

Keywords: Depression; Docosahexaenoic acid; Eicosapentaenoic acid; Omega-3 fatty acids; Omega-6 fatty acids; Patient Health Questionnaire-9; Screening.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cholesterol / blood
  • Chromatography, Gas / methods
  • Cross-Sectional Studies
  • Depression / blood*
  • Depression / physiopathology*
  • Diet / methods
  • Fatty Acids, Omega-3 / blood
  • Fatty Acids, Omega-6 / blood
  • Feeding Behavior / physiology*
  • Female
  • Humans
  • Lipids / blood
  • Male
  • Seafood
  • Surveys and Questionnaires
  • Triglycerides / blood

Substances

  • Fatty Acids, Omega-3
  • Fatty Acids, Omega-6
  • Lipids
  • Triglycerides
  • Cholesterol