Clostridium difficile colitis induced by cytarabine

Am J Clin Oncol. 1987 Oct;10(5):451-2. doi: 10.1097/00000421-198710000-00017.


Pseudomembranous enterocolitis (PMC) has become a widely recognized syndrome of nausea, abdominal distention, and severe (frequently bloody) diarrhea (1). While this syndrome was first associated with the administration of clindamycin, almost all antimicrobial drugs can serve as predisposing agents (2). We wish to report a patient with typical PMC induced by the administration of cytarabine.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cytarabine / adverse effects*
  • Cytarabine / therapeutic use
  • Enterocolitis, Pseudomembranous / chemically induced*
  • Enterocolitis, Pseudomembranous / diagnosis
  • Enterocolitis, Pseudomembranous / drug therapy
  • Humans
  • Leukemia, Myeloid / drug therapy
  • Male
  • Vancomycin / therapeutic use


  • Cytarabine
  • Vancomycin