A double-blind, placebo-controlled clinical study on the effect of a standardized ginseng extract on psychomotor performance in healthy volunteers

J Ethnopharmacol. 1986 Apr-May;16(1):15-22. doi: 10.1016/0378-8741(86)90063-2.


Various tests of psychomotor performance were carried out in a group of 16 healthy male volunteers given a standardized preparation of Korean ginseng (G 115; 100 mg twice a day for 12 weeks) and in a similar group given identical placebo capsules under double-blind conditions. A favourable effect of G 115 relative to baseline performance was observed in attention (cancellation test), processing (mental arithmetic, logical deduction), integrated sensory-motor function (choice reaction time) and auditory reaction time. However, end performance of the G 115 group was superior statistically to the placebo group only in mental arithmetic. No difference between G 115 and placebo was found in tests of pure motor function (tapping test), recognition (digit symbol substitution) and visual reaction time. No adverse effects were reported. It is concluded that G 115 may be superior to placebo in improving certain psychomotor functions in healthy subjects.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Clinical Trials as Topic
  • Double-Blind Method
  • Humans
  • Male
  • Panax / analysis*
  • Plant Extracts / pharmacology
  • Plants, Medicinal*
  • Psychomotor Performance / drug effects*
  • Random Allocation
  • Reaction Time / drug effects


  • Plant Extracts