Management of acute colonic pseudo-obstruction in a neutropenic patient

BMJ Case Rep. 2022 Jul 6;15(7):e250633. doi: 10.1136/bcr-2022-250633.

Abstract

Acute colonic pseudo-obstruction, also known as Ogilvie's syndrome, is a rare condition involving acute large bowel dilatation without mechanical obstruction. Management begins with conservative treatment and may include pharmacological therapy, colonoscopic decompression and surgery. Timely resolution is important due to the increased risk of bowel perforation and ischaemia associated with colonic dilatation. However, conditions such as neutropenia that place patients at an elevated risk of infection may limit treatment options. We report a case of acute colonic pseudo-obstruction in a neutropenic elderly man resistant to conservative measures and neostigmine and discuss the additional management considerations in an immunocompromised patient.

Keywords: Endoscopy; Medical management.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Colonic Pseudo-Obstruction* / complications
  • Colonic Pseudo-Obstruction* / therapy
  • Colonoscopes
  • Humans
  • Male
  • Neostigmine / therapeutic use
  • Neutropenia*

Substances

  • Neostigmine