Cultured epithelium as a skin substitute

Clin Plast Surg. 1985 Apr;12(2):149-57.


The history of techniques for the replacement of lost skin is reviewed, including the current research in the use of synthetic dermal substitutes, skin allografts and immunosuppression, and tissue-cultured epithelial autografts. Developments in each of these three areas are encouraging steps toward the development of a skin substitute that would be immediately available for coverage of even massive areas of skin loss.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Artificial Organs*
  • Burns / surgery
  • Cells, Cultured
  • Child
  • Child, Preschool
  • Epithelium*
  • Female
  • Graft Survival
  • Humans
  • Immunosuppression Therapy
  • Male
  • Membranes, Artificial
  • Skin / injuries*
  • Skin Transplantation
  • Surgery, Plastic*
  • Transplantation, Autologous
  • Wound Healing


  • Membranes, Artificial