The activities of monoamine oxidase-A and -B, succinate dehydrogenase and acid phosphatase in the rat brain after hemitransection

Naunyn Schmiedebergs Arch Pharmacol. 1981 Feb;316(1):51-5. doi: 10.1007/BF00507227.


The activities of monoamine oxidase-A and -B were determined in four brain regions (limbic system, occipito-temporal cortex, hemispheres and striatum) of the rat 0, 3, 6, 9 and 14 days after hemitransection of the left side. No larger or consistent change in the activity of monoamine oxidase-A towards 5-hydroxytryptamine was found for the left (hemitransected) side with respect to the right side for any of the rats. The monoamine oxidase-B activity towards beta-phenethylamine increased in the left side striatum to a significant level by 3 days, and in the hemispheres and occipito-temporal cortex on the left side, with respect to the right side by 9 days, but no significant changes were found for the limbic system. A small decrease in the activity of succinate dehydrogenase was found in the striatum on the left side by 9 days after hemitransection, but no change in the activity of acid phosphatase was found in this brain region.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acid Phosphatase / analysis*
  • Age Factors
  • Animals
  • Brain / enzymology*
  • Brain / surgery
  • Corpus Striatum / enzymology
  • Limbic System / enzymology
  • Male
  • Monoamine Oxidase / analysis*
  • Neurons / enzymology
  • Rats
  • Succinate Dehydrogenase / analysis*
  • Time Factors


  • Succinate Dehydrogenase
  • Monoamine Oxidase
  • Acid Phosphatase