Extensive congenital malformations in two siblings. Maternal pre-diabetes or a new syndrome?

Acta Paediatr Scand. 1981 Sep;70(5):767-9. doi: 10.1111/j.1651-2227.1981.tb05786.x.


Two sibs with similar and unusual abnormalities (skeletal malformations, cheilognatopalatoschizis, ear dysplasia, heart malformation) are described. The question as to whether these cases represent a previously undescribed recessive syndrome is discussed.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / etiology*
  • Abnormalities, Multiple / genetics
  • Adult
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Prediabetic State*
  • Pregnancy
  • Pregnancy in Diabetics / complications*