Nomenclature for N-acetyltransferases

Pharmacogenetics. 1995 Feb;5(1):1-17. doi: 10.1097/00008571-199502000-00001.


A consolidated classification system is described for prokaryotic and eukaryotic N-acetyltransferases in accordance with the international rules for gene nomenclature. The root symbol (NAT) specifically identifies the genes that code for the N-acetyltransferases, and NAT* loci encoding proteins with similar function are distinguished by Arabic numerals. Allele characters, denoted by Arabic numbers or by a combination of Arabic numbers and uppercase Latin letters, are separated from gene loci by an asterisk, and the entire gene-allele symbols are italicized. Alleles at the different NAT* loci have been numbered chronologically irrespective of the species of origin. For designation of genotypes at a single NAT* locus, a slash serves to separate the alleles; in phenotype designations, which are not italicized, alleles are separated by a comma.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alleles
  • Animals
  • Arylamine N-Acetyltransferase / classification*
  • Arylamine N-Acetyltransferase / genetics*
  • Biological Evolution
  • Chickens
  • Chromosome Mapping
  • Cricetinae
  • Genotype
  • Humans
  • Mesocricetus
  • Mice
  • Phenotype
  • Polymorphism, Genetic
  • Rabbits
  • Terminology as Topic*


  • Arylamine N-Acetyltransferase