Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1996;13(1-2):1-55.

Saponins as Vaccine Adjuvants

Affiliations
  • PMID: 8853958
Review

Saponins as Vaccine Adjuvants

C R Kensil. Crit Rev Ther Drug Carrier Syst. .

Abstract

Naturally occurring triterpene glycosides (saponins) from Quillaja saponaria have considerable adjuvant activity. Adjuvant functions include stimulation of high levels of antibody to T-dependent and T-independent antigens, induction of mouse IgG1, IgG2b, and IgG2a isotypes, and induction of cytotoxic T lymphocyte responses. This article reviews responses due to specific saponins of saponin preparations, effect of formulation, structure/function studies, and use in different preclinical and clinical vaccine applications.

Similar articles

See all similar articles

Cited by 50 articles

See all "Cited by" articles

MeSH terms

LinkOut - more resources

Feedback