New preparation and microstructure of the EndoPatch elastin-collagen containing glycosaminoglycans

Biomaterials. 1996 Sep;17(18):1813-8. doi: 10.1016/0142-9612(95)00346-0.

Abstract

Several improvements of the basic reaction between elastin-solubilized peptides and type I + III collagens are presented. They concern the prior incubation of the proteins in an adequate medium as well as the addition of heparan sulphate or hyaluronic acid (HA) and the consequent effects on the physical properties of yielded matrices. The addition of HA in small amounts enabled us to make membranes with good performances.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials*
  • Collagen / chemistry*
  • Elastin / chemistry*
  • Glycosaminoglycans / chemistry*
  • Heparitin Sulfate
  • Hyaluronic Acid
  • Microscopy, Electron, Scanning

Substances

  • Biocompatible Materials
  • Endopatch elastin-collagen
  • Glycosaminoglycans
  • Hyaluronic Acid
  • Collagen
  • Elastin
  • Heparitin Sulfate