The origin of interspersed repeats in the human genome

Curr Opin Genet Dev. 1996 Dec;6(6):743-8. doi: 10.1016/s0959-437x(96)80030-x.


Over a third of the human genome consists of interspersed repetitive sequences which are primarily degenerate copies of transposable elements. In the past year, the identities of many of these transposable elements were revealed. The emerging concept is that only three mechanisms of amplification are responsible for the vast majority of interspersed repeats and that with each autonomous element a number of dependent non-autonomous sequences have co-amplified.

Publication types

  • Review

MeSH terms

  • Animals
  • DNA Transposable Elements*
  • Genome, Human
  • Humans
  • Repetitive Sequences, Nucleic Acid*
  • Retroelements


  • DNA Transposable Elements
  • Retroelements