Postantibiotic effect assessments for antibiotics exhibiting a wide range of bactericidal activities by using a modified total-cell-counting method

Antimicrob Agents Chemother. 1997 May;41(5):1170-2. doi: 10.1128/AAC.41.5.1170.


We recently described a total-cell-counting method for postantibiotic effect (PAE) assessments that performs well with weakly bactericidal antibiotics. This note presents a modified method for the study of PAE with extended capability to cover a broad range of bactericidal activities.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Colony Count, Microbial / methods
  • Enterococcus faecalis / drug effects
  • Enterococcus faecalis / growth & development*
  • Pseudomonas aeruginosa / drug effects
  • Pseudomonas aeruginosa / growth & development*
  • Staphylococcus / drug effects
  • Staphylococcus / growth & development*


  • Anti-Bacterial Agents