Abstract
In a double-blind, parallel-group study of 135 patients with a mean age of 60 years, zopiclone 5 mg was compared with propiomazine 25 mg. The patients rated their sleep in a diary. There were statistically significant differences in favour of zopiclone for nine out of 13 variables measuring subjective sleep quality and quantity. Concerning side-effects, bad taste was reported more frequently in the zopiclone group and restless legs in the propiomazine group.
Publication types
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Clinical Trial
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Comparative Study
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Multicenter Study
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Randomized Controlled Trial
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Antipsychotic Agents / therapeutic use*
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Azabicyclo Compounds
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Double-Blind Method
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Female
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Humans
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Hypnotics and Sedatives / therapeutic use*
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Male
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Middle Aged
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Phenothiazines / therapeutic use*
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Piperazines / therapeutic use*
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Restless Legs Syndrome / chemically induced
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Sleep Initiation and Maintenance Disorders / drug therapy*
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Taste / drug effects
Substances
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Antipsychotic Agents
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Azabicyclo Compounds
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Hypnotics and Sedatives
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Phenothiazines
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Piperazines
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zopiclone
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propiomazine