Eurycoma Longifolia Jack Enhances Libido in Sexually Experienced Male Rats

Exp Anim. 1997 Oct;46(4):287-90. doi: 10.1538/expanim.46.287.

Abstract

The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 +/- 1.2, 4.9 +/- 0.7, 4.8 +/- 0.7 and 5.2 +/- 0.1, and 800 mg/kg further increased them to 5.4 +/- 0.8, 5.4 +/- 0.8, 5.2 +/- 0.6 and 5.3 +/- 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually vigorous male rats in the absence of feedback from genital sensation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aphrodisiacs / administration & dosage
  • Dose-Response Relationship, Drug
  • Libido*
  • Male
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plants, Medicinal*
  • Rats
  • Rats, Sprague-Dawley / psychology*
  • Sexual Behavior, Animal / drug effects*

Substances

  • Aphrodisiacs
  • Plant Extracts