Enhancement of oral absorption in selective 5-HT1D receptor agonists: fluorinated 3-[3-(piperidin-1-yl)propyl]indoles

J Med Chem. 1998 Jul 16;41(15):2667-70. doi: 10.1021/jm980204e.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • Administration, Oral
  • Animals
  • CHO Cells
  • Cricetinae
  • Humans
  • Indoles / administration & dosage
  • Indoles / chemical synthesis*
  • Indoles / pharmacology
  • Intestinal Absorption*
  • Piperidines / administration & dosage
  • Piperidines / chemical synthesis*
  • Piperidines / pharmacology
  • Receptor, Serotonin, 5-HT1D
  • Receptors, Serotonin / drug effects*
  • Receptors, Serotonin / metabolism
  • Recombinant Proteins / agonists
  • Recombinant Proteins / metabolism
  • Serotonin Receptor Agonists / administration & dosage
  • Serotonin Receptor Agonists / chemical synthesis*
  • Serotonin Receptor Agonists / pharmacology

Substances

  • Indoles
  • Piperidines
  • Receptor, Serotonin, 5-HT1D
  • Receptors, Serotonin
  • Recombinant Proteins
  • Serotonin Receptor Agonists