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The following term was not found in PubMed: Perityle
Unknown field was ignored: [orgn]
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Molecular cloning and sequence analysis of the sisomicin biosynthetic gene cluster from Micromonospora inyoensis.
Hong WR, Ge M, Zeng ZH, Zhu L, Luo MY, Shao L, Chen DJ. Hong WR, et al. Biotechnol Lett. 2009 Mar;31(3):449-55. doi: 10.1007/s10529-008-9887-y. Epub 2008 Nov 28. Biotechnol Lett. 2009. PMID: 19039528
Micromonospora inyoensis produces sisomicin (Sm), an aminoglycoside antibiotic. The gene cluster of sisomicin biosynthesis spanning ca. 47 kb consists of 37 ORFs encoding various proteins for sisomicin biosynthesis, regulation, resistance and transport. ...
Micromonospora inyoensis produces sisomicin (Sm), an aminoglycoside antibiotic. The gene cluster of sisomicin biosynthesis spanning c …
Enhanced Production of Sisomicin in Micromonospora inyoensis by Protoplast Mutagenesis and Fermentation Optimization.
Xu J, Shen S, Hu Z, Xu G, Li H, Xu Z, Shi J. Xu J, et al. Appl Biochem Biotechnol. 2024 Sep;196(9):6459-6472. doi: 10.1007/s12010-024-04889-4. Epub 2024 Feb 21. Appl Biochem Biotechnol. 2024. PMID: 38381313
In this study, to improve sisomicin production, breeding of high-yielding sisomicin strains was conducted with chemical mutagenesis using Micromonospora inyoensis OG-1 (titer, 1042 U.mL(-1)) as the starting strain. Protoplast preparation was conducted under optimal conditi …
In this study, to improve sisomicin production, breeding of high-yielding sisomicin strains was conducted with chemical mutagenesis using Mi …
Characterization in Micromonospora inyoensis of aminoglycoside acetyltransferase activity not previously encountered among actinomycetes.
Salas JA, Cundliffe E. Salas JA, et al. J Gen Microbiol. 1985 Mar;131(3):451-7. doi: 10.1099/00221287-131-3-451. J Gen Microbiol. 1985. PMID: 4020339
Extracts of Micromonospora inyoensis contain aminoglycoside acetyltransferase activity not previously encountered among actinomycetes. Neomycin and its derivatives (excluding butirosin) are good substrates as is the novel aminoglycoside apramycin, whereas the gentamicins a …
Extracts of Micromonospora inyoensis contain aminoglycoside acetyltransferase activity not previously encountered among actinomycetes …
Resolution of eleven reported and five novel Podaxis species based on ITS phylogeny, phylogenomics, morphology, ecology, and geographic distribution.
Li GS, Leal-Dutra CA, Cuesta-Maté A, Conlon BH, Peereboom N, Beemelmanns C, Aanen DK, Rosendahl S, de Beer ZW, Poulsen M. Li GS, et al. Persoonia. 2023 Jun;51:257-279. doi: 10.3767/persoonia.2023.51.07. Epub 2023 Dec 22. Persoonia. 2023. PMID: 38665980 Free PMC article.
Lastly, based on phylogenies and morphology of type material, we synonymized three reported species, P. algericus, P. arabicus, and P. rugospora with P. pistillaris, and described five new species that we named P. desolatus, P. inyoensis, P. mareebaensis, P. namaquensis, a …
Lastly, based on phylogenies and morphology of type material, we synonymized three reported species, P. algericus, P. arabicus, and P. rugos …
Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.
Noone P. Noone P. Drugs. 1984 Jun;27(6):548-78. doi: 10.2165/00003495-198427060-00003. Drugs. 1984. PMID: 6376062 Review.
Sisomicin is a naturally occurring aminoglycoside antibiotic produced by Micromonospora inyoensis, while dibekacin and netilmicin are both semisynthetic aminoglycosides. Dibekacin is 3',4'-dideoxykanamycin B and netilmicin is 1-N-ethyl sisomicin. ...
Sisomicin is a naturally occurring aminoglycoside antibiotic produced by Micromonospora inyoensis, while dibekacin and netilmicin are …
Semisynthetic aminoglycoside antibacterials. 6. Synthesis of sisomicin, Antibiotic G-52, and novel 6'-substituted analogues of sisomicin from aminoglycoside 66-40C.
Davies DH, Mallams AK, Counelis M, Loebenberg D, Moss EL Jr, Waitz JA. Davies DH, et al. J Med Chem. 1978 Feb;21(2):189-93. doi: 10.1021/jm00200a009. J Med Chem. 1978. PMID: 413921
The discovery of aminoglycoside 66-40C, a novel dimeric, unsaturated imine produced by Micromonospora inyoensis, afforded a versatile intermediate for the synthesis of a variety of sisomicin analogues modified at the 6' position. ...
The discovery of aminoglycoside 66-40C, a novel dimeric, unsaturated imine produced by Micromonospora inyoensis, afforded a versatile …
Cloning and characterization of the sisomicin-resistance gene from Micromonospora inyoensis.
Goldberg SL, Romero JG, Deo YM. Goldberg SL, et al. J Antibiot (Tokyo). 1990 Aug;43(8):992-9. doi: 10.7164/antibiotics.43.992. J Antibiot (Tokyo). 1990. PMID: 2211366 Free article.
We cloned DNA fragments of sisomicin-producing Micromonospora inyoensis into Streptomyces plasmid vectors and identified Streptomyces lividans TK24 transformants expressing the M. inyoensis sisomicin-resistance (sisA) gene. ...
We cloned DNA fragments of sisomicin-producing Micromonospora inyoensis into Streptomyces plasmid vectors and identified Streptomyces …
19 results