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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 4
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2002 2
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2006 7
2007 7
2008 5
2009 5
2010 3
2011 7
2012 10
2013 7
2014 5
2015 4
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2017 3
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2023 4
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115 results

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Page 1
SWAP70 Overexpression Protects Against Pathological Cardiac Hypertrophy in a TAK1-Dependent Manner.
Qian Q, Hu F, Yu W, Leng D, Li Y, Shi H, Deng D, Ding K, Liang C, Liu J. Qian Q, et al. J Am Heart Assoc. 2023 Apr 4;12(7):e028628. doi: 10.1161/JAHA.122.028628. Epub 2023 Mar 28. J Am Heart Assoc. 2023. PMID: 36974751 Free PMC article.
However, its role in pathological cardiac hypertrophy remains unclear. Methods and Results The effects of SWAP70 on pathological cardiac hypertrophy were investigated in Swap70 knockout mice and Swap70 overexpression/knockdown cardiomyocytes. ...TAK1 interact …
However, its role in pathological cardiac hypertrophy remains unclear. Methods and Results The effects of SWAP70 on pathological card …
SWAP70 is a universal GEF-like adaptor for tethering actin to phagosomes.
Baranov MV, Revelo NH, Verboogen DRJ, Ter Beest M, van den Bogaart G. Baranov MV, et al. Small GTPases. 2019 Jul;10(4):311-323. doi: 10.1080/21541248.2017.1328302. Epub 2018 Feb 9. Small GTPases. 2019. PMID: 28489960 Free PMC article.
In this study, we aimed to investigate whether this role of SWAP70 was general among immune phagocytes. Our data reveal that SWAP70 is recruited to early phagosomes of macrophages and dendritic cells from both human and mouse. The putative inhibitor of SWAP70 …
In this study, we aimed to investigate whether this role of SWAP70 was general among immune phagocytes. Our data reveal that SWAP7 …
SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis.
Baranov MV, Revelo NH, Dingjan I, Maraspini R, Ter Beest M, Honigmann A, van den Bogaart G. Baranov MV, et al. Cell Rep. 2016 Nov 1;17(6):1518-1531. doi: 10.1016/j.celrep.2016.10.021. Cell Rep. 2016. PMID: 27806292 Free PMC article.
Genetic ablation of SWAP70 impaired actin polymerization around phagosomes and resulted in a phagocytic defect. These data show a key role for SWAP70 as a scaffold for tethering the peripheral actin cage to phagosomes....
Genetic ablation of SWAP70 impaired actin polymerization around phagosomes and resulted in a phagocytic defect. These data show a key …
SWAP70 undergoes dynamic conformational regulation at the leading edge of migrating cells.
Kriplani N, Duncan RR, Leslie NR. Kriplani N, et al. FEBS Lett. 2019 Feb;593(4):395-405. doi: 10.1002/1873-3468.13326. Epub 2019 Jan 25. FEBS Lett. 2019. PMID: 30636036 Free article.
We have developed an encoded biosensor, which uses Forster resonance energy transfer to reveal conformational changes in SWAP70 in live cells. SWAP70 adopts a distinct conformation at the plasma membrane, which in migrating glioma cells is enriched at the leading ed …
We have developed an encoded biosensor, which uses Forster resonance energy transfer to reveal conformational changes in SWAP70 in li …
swap70 promotes neural precursor cell cycle exit and oligodendrocyte formation.
Takada N, Appel B. Takada N, et al. Mol Cell Neurosci. 2011 Nov;48(3):225-35. doi: 10.1016/j.mcn.2011.08.003. Epub 2011 Aug 12. Mol Cell Neurosci. 2011. PMID: 21875669 Free PMC article.
Our tests of gene function did not provide evidence that Swap70 regulates oligodendrocyte lineage cell behavior. Instead, we found that swap70 deficient larvae had excess neural precursors and a deficit of OPCs. Cells associated with neural proliferative zones expre …
Our tests of gene function did not provide evidence that Swap70 regulates oligodendrocyte lineage cell behavior. Instead, we found th …
Systemic proteome adaptions to 7-day complete caloric restriction in humans.
Pietzner M, Uluvar B, Kolnes KJ, Jeppesen PB, Frivold SV, Skattebo Ø, Johansen EI, Skålhegg BS, Wojtaszewski JFP, Kolnes AJ, Yeo GSH, O'Rahilly S, Jensen J, Langenberg C. Pietzner M, et al. Nat Metab. 2024 Apr;6(4):764-777. doi: 10.1038/s42255-024-01008-9. Epub 2024 Mar 1. Nat Metab. 2024. PMID: 38429390
Using proteogenomic approaches, we estimate the health consequences for 212 proteins that change during fasting across ~500 outcomes and identified putative beneficial (SWAP70 and rheumatoid arthritis or HYOU1 and heart disease), as well as adverse effects. ...
Using proteogenomic approaches, we estimate the health consequences for 212 proteins that change during fasting across ~500 outcomes and ide …
SWAP70, actin-binding protein, function as an oncogene targeting tumor-suppressive miR-145 in prostate cancer.
Chiyomaru T, Tatarano S, Kawakami K, Enokida H, Yoshino H, Nohata N, Fuse M, Seki N, Nakagawa M. Chiyomaru T, et al. Prostate. 2011 Oct 1;71(14):1559-67. doi: 10.1002/pros.21372. Epub 2011 Feb 25. Prostate. 2011. PMID: 21360565
A luciferase reporter assay was used to identify the actual binding sites between miR-145 and SWAP70 mRNA. Cell viability was evaluated by cell proliferation, wound healing, and matrigel invasion assays in si-SWAP70 transfectants. A total of 75 clinical prostate spe …
A luciferase reporter assay was used to identify the actual binding sites between miR-145 and SWAP70 mRNA. Cell viability was evaluat …
Switch-associated protein 70 protects against nonalcoholic fatty liver disease through suppression of TAK1.
Qian Q, Li Y, Fu J, Leng D, Dong Z, Shi J, Shi H, Cao D, Cheng X, Hu Y, Luo Q, Hu M, Ran Y, Tang H, Liu H, Liu J. Qian Q, et al. Hepatology. 2022 Jun;75(6):1507-1522. doi: 10.1002/hep.32213. Epub 2022 Apr 25. Hepatology. 2022. PMID: 34689362 Free PMC article.
However, the role of SWAP70 in NAFLD remains unclear. This study aimed to identify the function and mechanism of SWAP70 in NAFLD. ...Overexpression of SWAP70 in hepatocytes suppressed lipid deposition and inflammation, and SWAP70 knockdown created the …
However, the role of SWAP70 in NAFLD remains unclear. This study aimed to identify the function and mechanism of SWAP70 in NAF …
Promising therapeutic targets for ischemic stroke identified from plasma and cerebrospinal fluid proteomes: a multicenter Mendelian randomization study.
Zou X, Wang L, Wang S, Zhang Y, Ma J, Chen L, Li Y, Yao TX, Zhou H, Wu L, Tang Q, Ma S, Zhang X, Tang R, Yi Y, Liu R, Zeng Y, Zhang L. Zou X, et al. Int J Surg. 2024 Feb 1;110(2):766-776. doi: 10.1097/JS9.0000000000000922. Int J Surg. 2024. PMID: 38016292 Free PMC article.
Prekallikrein, MMP-12, SWAP70 was replicated in the FinnGen cohort and ISGC database. MMP-12 (OR=0.93, 95% CI: 0.91-0.94, P <0.001), SWAP70 (OR=0.92, 95% CI: 0.90-0.94, P <0.001), and prekallikrein (OR=0.53, 95% CI: 0.33-0.72, P <0.001) may all be viable ta …
Prekallikrein, MMP-12, SWAP70 was replicated in the FinnGen cohort and ISGC database. MMP-12 (OR=0.93, 95% CI: 0.91-0.94, P <0.001 …
The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity.
Dwyer J, Azzi S, Leclair HM, Georges S, Carlotti A, Treps L, Galan-Moya EM, Alexia C, Dupin N, Bidère N, Gavard J. Dwyer J, et al. Cell Commun Signal. 2015 Feb 15;13:11. doi: 10.1186/s12964-015-0090-1. Cell Commun Signal. 2015. PMID: 25889342 Free PMC article.
Examination of tissues and cells from HHV8-positive patients revealed that SWAP70 was ubiquitously expressed. Furthermore, SWAP70 was found to be crucial for vGPCR-driven endothelial tube formation and endothelial sprouting in vitro. CONCLUSIONS: SWAP70 appea …
Examination of tissues and cells from HHV8-positive patients revealed that SWAP70 was ubiquitously expressed. Furthermore, SWAP70 …
115 results