Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1892 1
1912 1
1913 1
1916 1
1922 2
1924 1
1926 2
1929 1
1930 1
1933 1
1934 2
1938 1
1944 1
1945 1
1946 3
1947 3
1948 18
1950 2
1951 2
1952 4
1953 11
1954 10
1955 9
1956 4
1957 8
1958 10
1959 5
1960 3
1961 6
1962 4
1963 13
1964 16
1965 13
1966 8
1967 9
1968 12
1969 17
1970 12
1971 27
1972 21
1973 22
1974 20
1975 87
1976 99
1977 97
1978 116
1979 151
1980 209
1981 190
1982 169
1983 253
1984 316
1985 340
1986 358
1987 459
1988 564
1989 722
1990 697
1991 806
1992 810
1993 915
1994 966
1995 974
1996 1096
1997 1109
1998 1119
1999 1304
2000 1524
2001 1598
2002 1551
2003 1766
2004 1794
2005 1896
2006 2141
2007 2347
2008 2498
2009 2556
2010 2690
2011 2826
2012 3076
2013 3345
2014 3537
2015 3837
2016 4194
2017 4843
2018 5419
2019 5503
2020 6519
2021 7408
2022 7259
2023 7140
2024 3372

Text availability

Article attribute

Article type

Publication date

Search Results

94,656 results

Results by year

Filters applied: . Clear all
The following term was ignored: |
Page 1
The hippocampal CA2 region is essential for social memory.
Hitti FL, Siegelbaum SA. Hitti FL, et al. Nature. 2014 Apr 3;508(7494):88-92. doi: 10.1038/nature13028. Epub 2014 Feb 23. Nature. 2014. PMID: 24572357 Free PMC article.
In the classic trisynaptic pathway, information proceeds from entorhinal cortex (EC) to dentate gyrus to CA3 and then to CA1, the main hippocampal output. Genetic lesions of EC (ref. 3) and hippocampal dentate gyrus (ref. 4), CA3 (ref. 5) and CA1 (ref. …
In the classic trisynaptic pathway, information proceeds from entorhinal cortex (EC) to dentate gyrus to CA3 and then to CA1, the main hippo …
Hyperparathyroidism-Jaw Tumor Syndrome.
Weaver TD, Shakir MKM, Hoang TD. Weaver TD, et al. Case Rep Oncol. 2021 Feb 18;14(1):29-33. doi: 10.1159/000510002. eCollection 2021 Jan-Apr. Case Rep Oncol. 2021. PMID: 33790762 Free PMC article.
The physical examination revealed a well-appearing Caucasian woman with no palpable neck mass. The laboratory results showed serum calcium at 11.7 mg/dL (ref. 8.4-10.2), ionized calcium at 1.44 mmol/L (ref. 1.12-1.32), and serum PTH at 192 pg/mL (ref. 11-65). …
The physical examination revealed a well-appearing Caucasian woman with no palpable neck mass. The laboratory results showed serum calcium a …
Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target Protein.
Choi S, Joo HK, Jeon BH. Choi S, et al. Chonnam Med J. 2016 May;52(2):75-80. doi: 10.4068/cmj.2016.52.2.75. Epub 2016 May 20. Chonnam Med J. 2016. PMID: 27231670 Free PMC article. Review.
Studies have identified a nuclear localization signal and a mitochondrial target sequence in APE1/Ref-1, as well as the involvement of the nuclear export system, as determinants of APE1/Ref-1 subcellular distribution. Recently, it was shown that APE1/Ref-1 is …
Studies have identified a nuclear localization signal and a mitochondrial target sequence in APE1/Ref-1, as well as the involvement o …
Functional dyspepsia.
Talley NJ, Goodsall T, Potter M. Talley NJ, et al. Aust Prescr. 2017 Dec;40(6):209-213. doi: 10.18773/austprescr.2017.066. Epub 2017 Dec 4. Aust Prescr. 2017. PMID: 29375182 Free PMC article. Review. No abstract available.
Going APE over ref-1.
Evans AR, Limp-Foster M, Kelley MR. Evans AR, et al. Mutat Res. 2000 Oct 16;461(2):83-108. doi: 10.1016/s0921-8777(00)00046-x. Mutat Res. 2000. PMID: 11018583 Review.
A crucial and the second step in the BER pathway involves the cleavage of baseless sites in DNA by an AP endonuclease. The major AP endonuclease in mammalian cells is Ape1/ref-1. Ape1/ref-1 is a multifunctional protein that is not only responsible for repair of AP s …
A crucial and the second step in the BER pathway involves the cleavage of baseless sites in DNA by an AP endonuclease. The major AP endonucl …
New Horizons for the Roles and Association of APE1/Ref-1 and ABCA1 in Atherosclerosis.
Chen W, Wang S, Xing D. Chen W, et al. J Inflamm Res. 2021 Oct 14;14:5251-5271. doi: 10.2147/JIR.S330147. eCollection 2021. J Inflamm Res. 2021. PMID: 34703267 Free PMC article. Review.
Interestingly, in addition to mediating these functions, ABCA1 promotes the secretion of acetylated APE1/Ref-1 (AcAPE1/Ref-1), a therapeutic target, which protects against atherosclerosis development. The APE1/Ref-1 inhibitor APX3330 is being evaluated in a p …
Interestingly, in addition to mediating these functions, ABCA1 promotes the secretion of acetylated APE1/Ref-1 (AcAPE1/Ref-1), …
APE1/Ref-1 as a Novel Target for Retinal Diseases.
Heisel C, Yousif J, Mijiti M, Charizanis K, Brigell M, Corson TW, Kelley MR. Heisel C, et al. J Cell Signal. 2021;2(2):133-138. doi: 10.33696/Signaling.2.044. J Cell Signal. 2021. PMID: 34322687 Free PMC article.
APE1/Ref-1 (also called Ref-1) has been extensively studied for its role in DNA repair and reduction-oxidation (redox) signaling. ...These pathways are highly implicated and validated as major players in DR, DME and AMD. Therefore, findings in cancer studies for …
APE1/Ref-1 (also called Ref-1) has been extensively studied for its role in DNA repair and reduction-oxidation (redox) signali …
APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions.
Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK. Thakur S, et al. Exp Mol Med. 2014 Jul 18;46(7):e106. doi: 10.1038/emm.2014.42. Exp Mol Med. 2014. PMID: 25033834 Free PMC article. Review.
Thus, APE1/Ref-1 acts as a 'hub-protein' that controls pathways that are important for cell survival. ...APE1/Ref-1 can be targeted for therapeutic intervention using natural plant products that modulate the expression and functions of APE1/Ref-1. ...
Thus, APE1/Ref-1 acts as a 'hub-protein' that controls pathways that are important for cell survival. ...APE1/Ref-1 can be tar …
Human APE/Ref-1 protein.
Fritz G. Fritz G. Int J Biochem Cell Biol. 2000 Sep;32(9):925-9. doi: 10.1016/s1357-2725(00)00045-5. Int J Biochem Cell Biol. 2000. PMID: 11084372 Review.
APE/Ref-1 is involved in the repair of DNA damage as well as in the transcriptional regulation of genes. ...Thus, specific downmodulation of APE/Ref-1 activity in tumors might be considered as a novel therapeutic approach in tumor therapy....
APE/Ref-1 is involved in the repair of DNA damage as well as in the transcriptional regulation of genes. ...Thus, specific downmodula …
Role of APE1/Ref-1 in hydrogen peroxide-induced apoptosis in human renal HK-2 cells.
Kim HY, Park JS, Jeon BH, Choi HS, Kim CS, Ma SK, Kim SW, Bae EH. Kim HY, et al. Kidney Res Clin Pract. 2024 Mar;43(2):186-201. doi: 10.23876/j.krcp.22.171. Epub 2023 May 23. Kidney Res Clin Pract. 2024. PMID: 37448293 Free PMC article.
The overexpression of APE1/Ref-1 with knockdown cell lines using an APE1/Ref-1-specific DNA or small interfering RNA (siRNA) was used for the apoptosis assay. ...The overexpression of APE1/Ref-1 in HK-2 cells enhanced the Bax/Bcl-2 ratio as a marker of apopto …
The overexpression of APE1/Ref-1 with knockdown cell lines using an APE1/Ref-1-specific DNA or small interfering RNA (siRNA) w …
94,656 results
You have reached the last available page of results. Please see the User Guide for more information.