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myung hyun jang[Author]
(4 results)?
APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells.
Br J Cancer. 2024 Jan;130(1):151-162. doi: 10.1038/s41416-023-02484-8. Epub 2023 Nov 15.
Br J Cancer. 2024.
PMID: 37968472
c-KIT regulates stability of cancer stemness in CD44-positive colorectal cancer cells.
Tomizawa F, Jang MK, Mashima T, Seimiya H.
Tomizawa F, et al. Among authors: jang mk.
Biochem Biophys Res Commun. 2020 Jul 5;527(4):1014-1020. doi: 10.1016/j.bbrc.2020.05.024. Epub 2020 May 18.
Biochem Biophys Res Commun. 2020.
PMID: 32439168
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Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.
Shirai F, Mizutani A, Yashiroda Y, Tsumura T, Kano Y, Muramatsu Y, Chikada T, Yuki H, Niwa H, Sato S, Washizuka K, Koda Y, Mazaki Y, Jang MK, Yoshida H, Nagamori A, Okue M, Watanabe T, Kitamura K, Shitara E, Honma T, Umehara T, Shirouzu M, Fukami T, Seimiya H, Yoshida M, Koyama H.
Shirai F, et al. Among authors: jang mk.
J Med Chem. 2020 Apr 23;63(8):4183-4204. doi: 10.1021/acs.jmedchem.0c00045. Epub 2020 Apr 1.
J Med Chem. 2020.
PMID: 32202790
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Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.
Jang MK, Mashima T, Seimiya H.
Jang MK, et al.
Mol Cancer Ther. 2020 Mar;19(3):765-776. doi: 10.1158/1535-7163.MCT-19-0668. Epub 2020 Jan 6.
Mol Cancer Ther. 2020.
PMID: 31907221
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Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo.
Mashima T, Wakatsuki T, Kawata N, Jang MK, Nagamori A, Yoshida H, Nakamura K, Migita T, Seimiya H, Yamaguchi K.
Mashima T, et al. Among authors: jang mk.
Sci Rep. 2021 Jul 23;11(1):15125. doi: 10.1038/s41598-021-94584-9.
Sci Rep. 2021.
PMID: 34302038
Free PMC article.
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mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.
Mashima T, Taneda Y, Jang MK, Mizutani A, Muramatsu Y, Yoshida H, Sato A, Tanaka N, Sugimoto Y, Seimiya H.
Mashima T, et al. Among authors: jang mk.
Oncotarget. 2017 Jul 18;8(29):47902-47915. doi: 10.18632/oncotarget.18146.
Oncotarget. 2017.
PMID: 28615517
Free PMC article.
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