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Potent inhibitors of protein farnesyltransferase: heteroarenes as cysteine replacements.
Shen W, Fakhoury S, Donner G, Henry K, Lee J, Zhang H, Cohen J, Warner R, Saeed B, Cherian S, Tahir S, Kovar P, Bauch J, Ng SC, Marsh K, Sham H, Rosenberg S. Shen W, et al. Among authors: saeed b. Bioorg Med Chem Lett. 1999 Mar 8;9(5):703-8. doi: 10.1016/s0960-894x(99)00080-3. Bioorg Med Chem Lett. 1999. PMID: 10201832
Second-generation peptidomimetic inhibitors of protein farnesyltransferase demonstrating improved cellular potency and significant in vivo efficacy.
O'Connor SJ, Barr KJ, Wang L, Sorensen BK, Tasker AS, Sham H, Ng SC, Cohen J, Devine E, Cherian S, Saeed B, Zhang H, Lee JY, Warner R, Tahir S, Kovar P, Ewing P, Alder J, Mitten M, Leal J, Marsh K, Bauch J, Hoffman DJ, Sebti SM, Rosenberg SH. O'Connor SJ, et al. Among authors: saeed b. J Med Chem. 1999 Sep 9;42(18):3701-10. doi: 10.1021/jm9901935. J Med Chem. 1999. PMID: 10479301
241 results