Bottomley MJ - Search Results

1

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphates.

Surdo PL, Bottomley MJ, Arcaro A, Siegal G, Panayotou G, Sankar A, Gaffney PR, Riley AM, Potter BV, Waterfield MD, Driscoll PC. Surdo PL, et al. Among authors: bottomley mj. J Biol Chem. 1999 May 28;274(22):15678-85. doi: 10.1074/jbc.274.22.15678. J Biol Chem. 1999. PMID: 10336465 Free article.

2

Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.

Salim K, Bottomley MJ, Querfurth E, Zvelebil MJ, Gout I, Scaife R, Margolis RL, Gigg R, Smith CI, Driscoll PC, Waterfield MD, Panayotou G. Salim K, et al. Among authors: bottomley mj. EMBO J. 1996 Nov 15;15(22):6241-50. EMBO J. 1996. PMID: 8947047 Free PMC article.

3

Intermolecular interactions of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase.

Harpur AG, Layton MJ, Das P, Bottomley MJ, Panayotou G, Driscoll PC, Waterfield MD. Harpur AG, et al. Among authors: bottomley mj. J Biol Chem. 1999 Apr 30;274(18):12323-32. doi: 10.1074/jbc.274.18.12323. J Biol Chem. 1999. PMID: 10212202 Free article.

4

Phospholipid-binding protein domains.

Bottomley MJ, Salim K, Panayotou G. Bottomley MJ, et al. Biochim Biophys Acta. 1998 Dec 8;1436(1-2):165-83. doi: 10.1016/s0005-2760(98)00141-6. Biochim Biophys Acta. 1998. PMID: 9838094 Review.

5

Endocytosis: How dynamin sets vesicles PHree!

Bottomley MJ, Lo Surdo P, Driscoll PC. Bottomley MJ, et al. Curr Biol. 1999 Apr 22;9(8):R301-4. doi: 10.1016/s0960-9822(99)80184-5. Curr Biol. 1999. PMID: 10226017 Free article. Review.

6

Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions.

Surdo PL, Bottomley MJ, Sattler M, Scheffzek K. Surdo PL, et al. Among authors: bottomley mj. Mol Endocrinol. 2003 Jul;17(7):1283-95. doi: 10.1210/me.2002-0409. Epub 2003 Apr 17. Mol Endocrinol. 2003. PMID: 12702733

7

Crystallization and preliminary X-ray diffraction characterisation of both a native and selenomethionyl VLA-4 binding fragment of VCAM-1.

Bottomley MJ, Robinson RC, Driscoll PC, Harlos K, Stuart DI, Aplin RT, Clements JM, Jones EY, Dudgeon TJ. Bottomley MJ, et al. J Mol Biol. 1994 Dec 9;244(4):464-8. doi: 10.1006/jmbi.1994.1743. J Mol Biol. 1994. PMID: 7527465

8

Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.

Jones EY, Harlos K, Bottomley MJ, Robinson RC, Driscoll PC, Edwards RM, Clements JM, Dudgeon TJ, Stuart DI. Jones EY, et al. Among authors: bottomley mj. Nature. 1995 Feb 9;373(6514):539-44. doi: 10.1038/373539a0. Nature. 1995. PMID: 7531291

9

Expression and characterisation of a very-late antigen-4 (alpha 4 beta 1) integrin-binding fragment of vascular cell-adhesion molecule-1.

Dudgeon TJ, Bottomley MJ, Driscoll PC, Humphries MJ, Mould AP, Wingfield GI, Clements JM. Dudgeon TJ, et al. Among authors: bottomley mj. Eur J Biochem. 1994 Dec 1;226(2):517-23. doi: 10.1111/j.1432-1033.1994.tb20076.x. Eur J Biochem. 1994. PMID: 7528140 Free article.

10

Structural and biochemical characterization of the wild type PCSK9-EGF(AB) complex and natural familial hypercholesterolemia mutants.

Bottomley MJ, Cirillo A, Orsatti L, Ruggeri L, Fisher TS, Santoro JC, Cummings RT, Cubbon RM, Lo Surdo P, Calzetta A, Noto A, Baysarowich J, Mattu M, Talamo F, De Francesco R, Sparrow CP, Sitlani A, Carfí A. Bottomley MJ, et al. J Biol Chem. 2009 Jan 9;284(2):1313-23. doi: 10.1074/jbc.M808363200. Epub 2008 Nov 10. J Biol Chem. 2009. PMID: 19001363 Free article.

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