Abe Y - Search Results

1

Nonpeptide mimic of bradykinin with long-acting properties.

Aramori I, Zenkoh J, Morikawa N, Asano M, Hatori C, Sawai H, Kayakiri H, Satoh S, Inoue T, Abe Y, Sawada Y, Mizutani T, Inamura N, Iwami M, Nakahara K, Kojo H, Oku T, Notsu Y. Aramori I, et al. Among authors: abe y. Immunopharmacology. 1999 Dec;45(1-3):185-90. doi: 10.1016/s0162-3109(99)00144-7. Immunopharmacology. 1999. PMID: 10615010

2

A new series of highly potent non-peptide bradykinin B2 receptor antagonists incorporating the 4-heteroarylquinoline framework. Improvement of aqueous solubility and new insights into species difference.

Sawada Y, Kayakiri H, Abe Y, Imai K, Mizutani T, Inamura N, Asano M, Aramori I, Hatori C, Katayama A, Oku T, Tanaka H. Sawada Y, et al. Among authors: abe y. J Med Chem. 2004 Mar 25;47(7):1617-30. doi: 10.1021/jm030159x. J Med Chem. 2004. PMID: 15027853

3

A new class of nonpeptide bradykinin B(2) receptor ligand, incorporating a 4-aminoquinoline framework. Identification of a key pharmacophore to determine species difference and agonist/antagonist profile.

Sawada Y, Kayakiri H, Abe Y, Mizutani T, Inamura N, Asano M, Aramori I, Hatori C, Oku T, Tanaka H. Sawada Y, et al. Among authors: abe y. J Med Chem. 2004 May 6;47(10):2667-77. doi: 10.1021/jm030326t. J Med Chem. 2004. PMID: 15115408

4

Discovery of the first non-peptide full agonists for the human bradykinin B(2) receptor incorporating 4-(2-picolyloxy)quinoline and 1-(2-picolyl)benzimidazole frameworks.

Sawada Y, Kayakiri H, Abe Y, Mizutani T, Inamura N, Asano M, Hatori C, Aramori I, Oku T, Tanaka H. Sawada Y, et al. Among authors: abe y. J Med Chem. 2004 May 20;47(11):2853-63. doi: 10.1021/jm030468n. J Med Chem. 2004. PMID: 15139763

5

The identification of an orally active, nonpeptide bradykinin B2 receptor antagonist, FR173657.

Asano M, Inamura N, Hatori C, Sawai H, Fujiwara T, Katayama A, Kayakiri H, Satoh S, Abe Y, Inoue T, Sawada Y, Nakahara K, Oku T, Okuhara M. Asano M, et al. Among authors: abe y. Br J Pharmacol. 1997 Feb;120(4):617-24. doi: 10.1038/sj.bjp.0700955. Br J Pharmacol. 1997. PMID: 9051299 Free PMC article.

6

Nonpeptide mimic of bradykinin with long-acting properties at the bradykinin B2 receptor.

Aramori I, Zenkoh J, Morikawa N, Asano M, Hatori C, Sawai H, Kayakiri H, Satoh S, Inoue T, Abe Y, Sawada Y, Mizutani T, Inamura N, Nakahara K, Kojo H, Oku T, Notsu Y. Aramori I, et al. Among authors: abe y. Mol Pharmacol. 1997 Jul;52(1):16-20. doi: 10.1124/mol.52.1.16. Mol Pharmacol. 1997. PMID: 9224807

7

Pharmacological characterization of a novel, orally active, nonpeptide bradykinin B2 receptor antagonist, FR167344.

Inamura N, Asano M, Hatori C, Sawai H, Hirosumi J, Fujiwara T, Kayakiri H, Satoh S, Abe Y, Inoue T, Sawada Y, Oku T, Nakahara K. Inamura N, et al. Among authors: abe y. Eur J Pharmacol. 1997 Aug 20;333(1):79-86. doi: 10.1016/s0014-2999(97)01100-x. Eur J Pharmacol. 1997. PMID: 9311664

8

Pharmacological characterization of a nonpeptide bradykinin B2 receptor antagonist, FR165649, and agonist, FR190997.

Asano M, Hatori C, Sawai H, Johki S, Inamura N, Kayakiri H, Satoh S, Abe Y, Inoue T, Sawada Y, Mizutani T, Oku T, Nakahara K. Asano M, et al. Among authors: abe y. Br J Pharmacol. 1998 Jun;124(3):441-6. doi: 10.1038/sj.bjp.0701813. Br J Pharmacol. 1998. PMID: 9647466 Free PMC article.

9

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 2. Overcoming the species difference between guinea pig and man.

Abe Y, Kayakiri H, Satoh S, Inoue T, Sawada Y, Inamura N, Asano M, Hatori C, Sawai H, Oku T, Tanaka H. Abe Y, et al. J Med Chem. 1998 Oct 8;41(21):4053-61. doi: 10.1021/jm980214f. J Med Chem. 1998. PMID: 9767642

10

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 3. Discovering bioisosteres of the imidazo[1,2-a] pyridine moiety.

Abe Y, Kayakiri H, Satoh S, Inoue T, Sawada Y, Inamura N, Asano M, Aramori I, Hatori C, Sawai H, Oku T, Tanaka H. Abe Y, et al. J Med Chem. 1998 Oct 8;41(21):4062-79. doi: 10.1021/jm980300f. J Med Chem. 1998. PMID: 9767643

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