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Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390: a lead HIV protease inhibitor.
Prasad JV, Boyer FE, Domagala JM, Ellsworth EL, Gajda C, Hamilton HW, Hagen SE, Markoski LJ, Steinbaugh BA, Tait BD, Humblet C, Lunney EA, Pavlovsky A, Rubin JR, Ferguson D, Graham N, Holler T, Hupe D, Nouhan C, Tummino PJ, Urumov A, Zeikus E, Zeikus G, Gracheck SJ, Erickson JW, et al. Prasad JV, et al. Among authors: zeikus e. Bioorg Med Chem. 1999 Dec;7(12):2775-800. doi: 10.1016/s0968-0896(99)00215-1. Bioorg Med Chem. 1999. PMID: 10658583
5,6-Dihydropyran-2-ones possessing various sulfonyl functionalities: potent nonpeptidic inhibitors of HIV protease.
Boyer FE, Vara Prasad JV, Domagala JM, Ellsworth EL, Gajda C, Hagen SE, Markoski LJ, Tait BD, Lunney EA, Palovsky A, Ferguson D, Graham N, Holler T, Hupe D, Nouhan C, Tummino PJ, Urumov A, Zeikus E, Zeikus G, Gracheck SJ, Sanders JM, VanderRoest S, Brodfuehrer J, Iyer K, Sinz M, Gulnik SV. Boyer FE, et al. Among authors: zeikus e. J Med Chem. 2000 Mar 9;43(5):843-58. doi: 10.1021/jm990281p. J Med Chem. 2000. PMID: 10715152
4-Hydroxy-5,6-dihydropyrones as inhibitors of HIV protease: the effect of heterocyclic substituents at C-6 on antiviral potency and pharmacokinetic parameters.
Hagen SE, Domagala J, Gajda C, Lovdahl M, Tait BD, Wise E, Holler T, Hupe D, Nouhan C, Urumov A, Zeikus G, Zeikus E, Lunney EA, Pavlovsky A, Gracheck SJ, Saunders J, VanderRoest S, Brodfuehrer J. Hagen SE, et al. Among authors: zeikus e. J Med Chem. 2001 Jul 5;44(14):2319-32. doi: 10.1021/jm0003844. J Med Chem. 2001. PMID: 11428926
What the Baby Formula and Medical Contrast Material Shortages Have in Common: Insights and Recommendations for Managing the Iodinated Contrast Media Shortage.
Ananthakrishnan L, Kay FU, Zeikus EA, Chu ES, Chang J, Barr JD, Rofsky NM, Abbara S. Ananthakrishnan L, et al. Among authors: zeikus ea. Radiol Cardiothorac Imaging. 2022 May 25;4(3):e220101. doi: 10.1148/ryct.220101. eCollection 2022 Jun. Radiol Cardiothorac Imaging. 2022. PMID: 35833167 Free PMC article.
Response to COVID-19: Minimizing Risks, Addressing Challenges and Maintaining Operations in a Complex Academic Radiology Department.
Pedrosa I, Browning T, Kwon JK, Morriss M, Matsler L, Pinho MC, Lamus D, Pillai A, Karow SP, Garinn J, Brewington C, Zeikus E, Rofsky NM. Pedrosa I, et al. Among authors: zeikus e. J Comput Assist Tomogr. 2020 Jul/Aug;44(4):479-484. doi: 10.1097/RCT.0000000000001040. J Comput Assist Tomogr. 2020. PMID: 32433251 Free PMC article.