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Nonsecreted insulin-like growth factor binding protein-3 (IGFBP-3) can induce apoptosis in human prostate cancer cells by IGF-independent mechanisms without being concentrated in the nucleus.
Bhattacharyya N, Pechhold K, Shahjee H, Zappala G, Elbi C, Raaka B, Wiench M, Hong J, Rechler MM. Bhattacharyya N, et al. Among authors: rechler mm. J Biol Chem. 2006 Aug 25;281(34):24588-601. doi: 10.1074/jbc.M509463200. Epub 2006 Jun 22. J Biol Chem. 2006. PMID: 16793770 Free article.
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