Keeling SE - Search Results

1

The discovery and synthesis of highly potent, A2a receptor agonists.

Keeling SE, Albinson FD, Ayres BE, Butchers PR, Chambers CL, Cherry PC, Ellis F, Ewan GB, Gregson M, Knight J, Mills K, Ravenscroft P, Reynolds LH, Sanjar S, Sheehan MJ. Keeling SE, et al. Bioorg Med Chem Lett. 2000 Feb 21;10(4):403-6. doi: 10.1016/s0960-894x(00)00017-2. Bioorg Med Chem Lett. 2000. PMID: 10714510

2

The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors.

Chan C, Andreotti D, Cox B, Dymock BW, Hutson JL, Keeling SE, McCarthy AD, Procopiou PA, Ross BC, Sareen M, Scicinski JJ, Sharratt PJ, Snowden MA, Watson NS. Chan C, et al. Among authors: keeling se. J Med Chem. 1996 Jan 5;39(1):207-16. doi: 10.1021/jm9504969. J Med Chem. 1996. PMID: 8568810

3

Pyrazolopyridines as potent PDE4B inhibitors: 5-heterocycle SAR.

Mitchell CJ, Ballantine SP, Coe DM, Cook CM, Delves CJ, Dowle MD, Edlin CD, Hamblin JN, Holman S, Johnson MR, Jones PS, Keeling SE, Kranz M, Lindvall M, Lucas FS, Neu M, Solanke YE, Somers DO, Trivedi NA, Wiseman JO. Mitchell CJ, et al. Among authors: keeling se. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5803-6. doi: 10.1016/j.bmcl.2010.07.136. Epub 2010 Aug 5. Bioorg Med Chem Lett. 2010. PMID: 20732811

4

Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors.

Chan C, Bailey EJ, Hartley CD, Hayman DF, Hutson JL, Inglis GG, Jones PS, Keeling SE, Kirk BE, Lamont RB, et al. Chan C, et al. Among authors: keeling se. J Med Chem. 1993 Nov 12;36(23):3646-57. doi: 10.1021/jm00075a020. J Med Chem. 1993. PMID: 8246233

5

Optimisation and validation of a PCR to detect viable Tenacibaculum maritimum in salmon skin tissue samples.

Brosnahan CL, Georgiades E, McDonald C, Keeling SE, Munday JS, Jones B. Brosnahan CL, et al. Among authors: keeling se. J Microbiol Methods. 2019 Apr;159:186-193. doi: 10.1016/j.mimet.2019.03.008. Epub 2019 Mar 12. J Microbiol Methods. 2019. PMID: 30877014

6

Using chemical and DNA marker analysis to authenticate a high-value food, manuka honey.

McDonald CM, Keeling SE, Brewer MJ, Hathaway SC. McDonald CM, et al. Among authors: keeling se. NPJ Sci Food. 2018 May 22;2:9. doi: 10.1038/s41538-018-0016-6. eCollection 2018. NPJ Sci Food. 2018. PMID: 31304259 Free PMC article.

7

Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3-Kinase δ for the Treatment of Respiratory Disease.

Down K, Amour A, Baldwin IR, Cooper AW, Deakin AM, Felton LM, Guntrip SB, Hardy C, Harrison ZA, Jones KL, Jones P, Keeling SE, Le J, Livia S, Lucas F, Lunniss CJ, Parr NJ, Robinson E, Rowland P, Smith S, Thomas DA, Vitulli G, Washio Y, Hamblin JN. Down K, et al. Among authors: keeling se. J Med Chem. 2015 Sep 24;58(18):7381-99. doi: 10.1021/acs.jmedchem.5b00767. Epub 2015 Sep 3. J Med Chem. 2015. PMID: 26301626

8

Design of a detection survey for Ostreid herpesvirus-1 using hydrodynamic dispersion models to determine epidemiological units.

Pande A, Acosta H, Brangenberg NA, Keeling SE. Pande A, et al. Among authors: keeling se. Prev Vet Med. 2015 Apr 1;119(1-2):80-4. doi: 10.1016/j.prevetmed.2015.02.009. Epub 2015 Feb 21. Prev Vet Med. 2015. PMID: 25746929

9

New Zealand juvenile oyster mortality associated with ostreid herpesvirus 1-an opportunistic longitudinal study.

Keeling SE, Brosnahan CL, Williams R, Gias E, Hannah M, Bueno R, McDonald WL, Johnston C. Keeling SE, et al. Dis Aquat Organ. 2014 Jul 3;109(3):231-9. doi: 10.3354/dao02735. Dis Aquat Organ. 2014. PMID: 24991849 Free article.

10

Development and validation of a real-time PCR assay for the detection of Aeromonas salmonicida.

Keeling SE, Brosnahan CL, Johnston C, Wallis R, Gudkovs N, McDonald WL. Keeling SE, et al. J Fish Dis. 2013 May;36(5):495-503. doi: 10.1111/jfd.12014. Epub 2012 Nov 5. J Fish Dis. 2013. PMID: 23121198

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