Sheehan MJ - Search Results

1

The discovery and synthesis of highly potent, A2a receptor agonists.

Keeling SE, Albinson FD, Ayres BE, Butchers PR, Chambers CL, Cherry PC, Ellis F, Ewan GB, Gregson M, Knight J, Mills K, Ravenscroft P, Reynolds LH, Sanjar S, Sheehan MJ. Keeling SE, et al. Among authors: sheehan mj. Bioorg Med Chem Lett. 2000 Feb 21;10(4):403-6. doi: 10.1016/s0960-894x(00)00017-2. Bioorg Med Chem Lett. 2000. PMID: 10714510

2

Studies on the effects of adenosine A3 receptor stimulation on human eosinophils isolated from non-asthmatic or asthmatic donors.

Reeves JJ, Harris CA, Hayes BP, Butchers PR, Sheehan MJ. Reeves JJ, et al. Among authors: sheehan mj. Inflamm Res. 2000 Dec;49(12):666-72. doi: 10.1007/s000110050644. Inflamm Res. 2000. PMID: 11211916

3

The effect of adenosine and its analogues on histamine release from mast cells.

Dexter EJ, Butchers PR, Reeves JJ, Sheehan MJ, Pearce FL. Dexter EJ, et al. Among authors: sheehan mj. Inflamm Res. 1999 Apr;48 Suppl 1:S7-8. doi: 10.1007/s000110050371. Inflamm Res. 1999. PMID: 10350137 No abstract available.

4

Synthesis, antinociceptive activity, and opioid receptor profiles of substituted trans-3-(decahydro- and octahydro-4a-isoquinolinyl)phenols.

Judd DB, Brown DS, Lloyd JE, McElroy AB, Scopes DI, Birch PJ, Hayes AG, Sheehan MJ. Judd DB, et al. Among authors: sheehan mj. J Med Chem. 1992 Jan;35(1):48-56. doi: 10.1021/jm00079a005. J Med Chem. 1992. PMID: 1310115

5

Failure of CGS15943A to block the hypotensive action of agonists acting at the adenosine A3 receptor.

Patel M, Sheehan MJ, Strong P. Patel M, et al. Among authors: sheehan mj. Br J Pharmacol. 1994 Nov;113(3):741-8. doi: 10.1111/j.1476-5381.1994.tb17056.x. Br J Pharmacol. 1994. PMID: 7858863 Free PMC article.

6

Pharmacological characterisation and inhibitory effects of (2R,3R,4S,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol, a novel ligand that demonstrates both adenosine A(2A) receptor agonist and adenosine A(3) receptor antagonist activity.

Bevan N, Butchers PR, Cousins R, Coates J, Edgar EV, Morrison V, Sheehan MJ, Reeves J, Wilson DJ. Bevan N, et al. Among authors: sheehan mj. Eur J Pharmacol. 2007 Jun 14;564(1-3):219-25. doi: 10.1016/j.ejphar.2007.01.094. Epub 2007 Feb 16. Eur J Pharmacol. 2007. PMID: 17382926

7

Comparative analysis of the efficacy of A1 adenosine receptor activation of Gi/o alpha G proteins following coexpression of receptor and G protein and expression of A1 adenosine receptor-Gi/o alpha fusion proteins.

Wise A, Sheehan M, Rees S, Lee M, Milligan G. Wise A, et al. Biochemistry. 1999 Feb 23;38(8):2272-8. doi: 10.1021/bi982054f. Biochemistry. 1999. PMID: 10029519

8

Adenosine A3 receptors promote degranulation of rat mast cells both in vitro and in vivo.

Reeves JJ, Jones CA, Sheehan MJ, Vardey CJ, Whelan CJ. Reeves JJ, et al. Among authors: sheehan mj. Inflamm Res. 1997 May;46(5):180-4. doi: 10.1007/s000110050169. Inflamm Res. 1997. PMID: 9197988

9

Characterization of the adenosine receptors mediating hypothermia in the conscious mouse.

Anderson R, Sheehan MJ, Strong P. Anderson R, et al. Among authors: sheehan mj. Br J Pharmacol. 1994 Dec;113(4):1386-90. doi: 10.1111/j.1476-5381.1994.tb17151.x. Br J Pharmacol. 1994. PMID: 7889296 Free PMC article.

10

Characterization of the prejunctional adenosine receptors in the rat anococcygeus muscle.

Coates J, Green MA, Sheehan MJ, Strong P. Coates J, et al. Among authors: sheehan mj. J Pharm Pharmacol. 1994 Nov;46(11):906-10. doi: 10.1111/j.2042-7158.1994.tb05712.x. J Pharm Pharmacol. 1994. PMID: 7897597

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