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Kaposi's sarcoma-associated herpesvirus-induced upregulation of the c-kit proto-oncogene, as identified by gene expression profiling, is essential for the transformation of endothelial cells.
Moses AV, Jarvis MA, Raggo C, Bell YC, Ruhl R, Luukkonen BG, Griffith DJ, Wait CL, Druker BJ, Heinrich MC, Nelson JA, Früh K. Moses AV, et al. Among authors: wait cl. J Virol. 2002 Aug;76(16):8383-99. doi: 10.1128/jvi.76.16.8383-8399.2002. J Virol. 2002. PMID: 12134042 Free PMC article.
KIT mutations are common in testicular seminomas.
Kemmer K, Corless CL, Fletcher JA, McGreevey L, Haley A, Griffith D, Cummings OW, Wait C, Town A, Heinrich MC. Kemmer K, et al. Among authors: wait c. Am J Pathol. 2004 Jan;164(1):305-13. doi: 10.1016/S0002-9440(10)63120-3. Am J Pathol. 2004. PMID: 14695343 Free PMC article.
A functional genomics approach to Kaposi's sarcoma.
Moses AV, Jarvis MA, Raggo C, Bell YC, Ruhl R, Luukkonen BG, Griffith DJ, Wait CL, Druker BJ, Heinrich MC, Nelson JA, Fruh K. Moses AV, et al. Among authors: wait cl. Ann N Y Acad Sci. 2002 Dec;975:180-91. doi: 10.1111/j.1749-6632.2002.tb05951.x. Ann N Y Acad Sci. 2002. PMID: 12538164