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Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer.
Kooy-Winkelaar Y, van Lummel M, Moustakas AK, Schweizer J, Mearin ML, Mulder CJ, Roep BO, Drijfhout JW, Papadopoulos GK, van Bergen J, Koning F. Kooy-Winkelaar Y, et al. Among authors: koning f. J Immunol. 2011 Nov 15;187(10):5123-9. doi: 10.4049/jimmunol.1101179. Epub 2011 Oct 17. J Immunol. 2011. PMID: 22013116
Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire.
van Lummel M, van Veelen PA, Zaldumbide A, de Ru A, Janssen GM, Moustakas AK, Papadopoulos GK, Drijfhout JW, Roep BO, Koning F. van Lummel M, et al. Among authors: koning f. J Biol Chem. 2012 Mar 16;287(12):9514-24. doi: 10.1074/jbc.M111.313940. Epub 2011 Dec 19. J Biol Chem. 2012. PMID: 22184118 Free PMC article.
Crossreactivity to vinculin and microbes provides a molecular basis for HLA-based protection against rheumatoid arthritis.
van Heemst J, Jansen DT, Polydorides S, Moustakas AK, Bax M, Feitsma AL, Bontrop-Elferink DG, Baarse M, van der Woude D, Wolbink GJ, Rispens T, Koning F, de Vries RR, Papadopoulos GK, Archontis G, Huizinga TW, Toes RE. van Heemst J, et al. Among authors: koning f. Nat Commun. 2015 May 5;6:6681. doi: 10.1038/ncomms7681. Nat Commun. 2015. PMID: 25942574 Free article.
345 results