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The molecular and enzyme kinetic basis for the diminished activity of the cytochrome P450 2D6.17 (CYP2D6.17) variant. Potential implications for CYP2D6 phenotyping studies and the clinical use of CYP2D6 substrate drugs in some African populations.
Bapiro TE, Hasler JA, Ridderström M, Masimirembwa CM. Bapiro TE, et al. Among authors: masimirembwa cm. Biochem Pharmacol. 2002 Nov 1;64(9):1387-98. doi: 10.1016/s0006-2952(02)01351-5. Biochem Pharmacol. 2002. PMID: 12392820
Low CYP1A2 activity in rural Shona children of Zimbabwe.
Masimirembwa CM, Beke M, Hasler JA, Tang BK, Kalow W. Masimirembwa CM, et al. Clin Pharmacol Ther. 1995 Jan;57(1):25-31. doi: 10.1016/0009-9236(95)90262-7. Clin Pharmacol Ther. 1995. PMID: 7828378
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