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90 results

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Page 1
Plasma versus tissue tumor mutational burden as biomarkers of durvalumab plus tremelimumab response in patients with metastatic colorectal cancer in the CO.26 trial.
Loree JM, Titmuss E, Topham JT, Kennecke HF, Feilotter H, Virk S, Lee YS, Banks K, Quinn K, Karsan A, Renouf DJ, Jonker DJ, Tu D, O'Callaghan CJ, Chen EX. Loree JM, et al. Among authors: topham jt. Clin Cancer Res. 2024 May 10. doi: 10.1158/1078-0432.CCR-24-0268. Online ahead of print. Clin Cancer Res. 2024. PMID: 38727700
Nutrient scavenging-fueled growth in pancreatic cancer depends on caveolae-mediated endocytosis under nutrient-deprived conditions.
Wolfe AR, Cui T, Baie S, Corrales-Guerrero S, Webb A, Castro-Aceituno V, Shyu DL, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Halloran M, Packard R, Robb R, Chen W, Denko N, Lisanti M, Thompson TC, Frank P, Williams TM. Wolfe AR, et al. Among authors: topham jt. Sci Adv. 2024 Mar;10(9):eadj3551. doi: 10.1126/sciadv.adj3551. Epub 2024 Mar 1. Sci Adv. 2024. PMID: 38427741 Free PMC article.
Optimizing the number of variants tracked to follow disease burden with circulating tumor DNA assays in metastatic colorectal cancer.
Boutin M, Topham JT, Feilotter H, Kennecke HF, Couture F, Harb M, Kavan P, Berry S, Lim HJ, Goffin JR, Ahmad C, Lott A, Renouf DJ, Jonker DJ, Tu D, O'Callaghan CJ, Chen EX, Loree JM. Boutin M, et al. Among authors: topham jt. Ther Adv Med Oncol. 2023 Jun 22;15:17588359231183682. doi: 10.1177/17588359231183682. eCollection 2023. Ther Adv Med Oncol. 2023. PMID: 37389190 Free PMC article.
Feasibility and value of genomic profiling in cancer of unknown primary: real-world evidence from prospective profiling study.
Huey RW, Shah AT, Reddi HV, Dasari P, Topham JT, Hwang H, Dhillon N, Willett A, Smaglo BG, Estrella JS, Rashid A, Matamoros A, Overman MJ, Choquette L, Omerza G, Kelly K, Wang X, Loree JM, Rueter J, Varadhachary GR, Raghav K. Huey RW, et al. Among authors: topham jt. J Natl Cancer Inst. 2023 Aug 8;115(8):994-997. doi: 10.1093/jnci/djad095. J Natl Cancer Inst. 2023. PMID: 37202363 Free PMC article. Clinical Trial.
Immune Activation following Irbesartan Treatment in a Colorectal Cancer Patient: A Case Study.
Titmuss E, Milne K, Jones MR, Ng T, Topham JT, Brown SD, Schaeffer DF, Kalloger S, Wilson D, Corbett RD, Williamson LM, Mungall K, Mungall AJ, Holt RA, Nelson BH, Jones SJM, Laskin J, Lim HJ, Marra MA. Titmuss E, et al. Among authors: topham jt. Int J Mol Sci. 2023 Mar 20;24(6):5869. doi: 10.3390/ijms24065869. Int J Mol Sci. 2023. PMID: 36982943 Free PMC article.
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration.
Tsang ES, Csizmok V, Williamson LM, Pleasance E, Topham JT, Karasinska JM, Titmuss E, Schrader I, Yip S, Tessier-Cloutier B, Mungall K, Ng T, Sun S, Lim HJ, Loree JM, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Tsang ES, et al. Among authors: topham jt. NPJ Precis Oncol. 2023 Mar 24;7(1):31. doi: 10.1038/s41698-023-00368-x. NPJ Precis Oncol. 2023. PMID: 36964191 Free PMC article.
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.
Topham JT, Tsang ES, Karasinska JM, Metcalfe A, Ali H, Kalloger SE, Csizmok V, Williamson LM, Titmuss E, Nielsen K, Negri GL, Spencer Miko SE, Jang GH, Denroche RE, Wong HL, O'Kane GM, Moore RA, Mungall AJ, Loree JM, Notta F, Wilson JM, Bathe OF, Tang PA, Goodwin R, Morin GB, Knox JJ, Gallinger S, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Topham JT, et al. Nat Commun. 2022 Oct 8;13(1):5941. doi: 10.1038/s41467-022-33718-7. Nat Commun. 2022. PMID: 36209277 Free PMC article.
The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma.
Renouf DJ, Loree JM, Knox JJ, Topham JT, Kavan P, Jonker D, Welch S, Couture F, Lemay F, Tehfe M, Harb M, Aucoin N, Ko YJ, Tang PA, Ramjeesingh R, Meyers BM, Kim CA, Du P, Jia S, Schaeffer DF, Gill S, Tu D, O'Callaghan CJ. Renouf DJ, et al. Among authors: topham jt. Nat Commun. 2022 Aug 26;13(1):5020. doi: 10.1038/s41467-022-32591-8. Nat Commun. 2022. PMID: 36028483 Free PMC article. Clinical Trial.
90 results